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PodMine

Greg Brockman

Matches in: Person
12 episodes
Jan 7, 2026• Prof G Markets

Can a GLP-1 Pill Revive Novo Nordisk?

A deep dive into Novo Nordisk's groundbreaking first-ever GLP-1 pill for weight loss, exploring its potential market impact, pricing strategy, and the broader implications for obesity treatment in the United States.

30:53
Dec 19, 2025• "The Cognitive Revolution" | AI Builders, Researchers, and Live Player Analysis

AI 2025 → 2026 Live Show | Part 2

A live podcast episode featuring conversations with Alex Boris, Dean Ball, and Peter Wildeford exploring AI developments, policy challenges, and forecasts for 2026, covering topics like the RAISE Act, chip sales to China, AI agent capabilities, and potential technological paradigm shifts.

1:39:36
Dec 1, 2025• Core Memory

OpenAI's Research Chief On The Soup Wars, Poker And The Next Models - EP 46 Mark Chen

Mark Chen, OpenAI's Chief Research Officer, discusses the company's research priorities, talent recruitment, competitive landscape in AI, and his optimistic view on the potential of AI to drive scientific discovery and potentially reach AGI within the next few years.

1:38:18
Nov 28, 2025• a16z Podcast

How OpenAI Builds for 800 Million Weekly Users: Model Specialization and Fine-Tuning

A deep dive into how OpenAI is shifting from a single general-purpose model to a portfolio of specialized systems, discussing model customization, fine-tuning, agent workflows, and the evolving landscape of AI platforms.

53:24
Nov 13, 2025• This Week in Startups

Why We Need Ferries and Tugboats in Space w/ Orbital Operations | E2208

A podcast episode exploring space logistics with Orbital Operations, discussing their innovative cryogenic orbital maneuvering vehicle (Astraeus) designed to efficiently transport satellites between different orbits, while also highlighting potential dual-use military and commercial applications.

1:13:56
Nov 5, 2025• a16z Podcast

Seeing The Future from AI Companions to Personal Software

In this episode, Eugenia Kuyda discusses how personal software will transform from a developer monopoly to a creative medium where anyone can create, remix, and share mini-apps as easily as posting a video, focusing on deep personalization and making AI interfaces more intuitive and accessible.

50:20
Oct 15, 2025• Core Memory

He's Building A Space Station For $1 Billion - EP 38 Jed McCaleb

Jed McCaleb discusses his journey from peer-to-peer file sharing to cryptocurrency and now building VAST, a space station company aiming to create commercial habitats in low Earth orbit with a billion-dollar personal investment.

1:12:44
Oct 10, 2025• Hard Fork

ChatGPT’s Platform Play + a Trillion-Dollar GPU Empire + the Queen of Slop

Kevin Roose and Casey Newton explore OpenAI's developer day announcements, including ChatGPT's platform strategy, their massive GPU infrastructure deals, and a humorous discussion with Katie Natopoulos about AI-generated video slop.

1:06:35
Oct 8, 2025• We Study Billionaires - The Investor’s Podcast Network

TECH004: Sam Altman & the Rise of OpenAI w/ Seb Bunney

A deep dive into Sam Altman's journey with OpenAI, exploring its transformation from a nonprofit vision to a Microsoft-backed AI powerhouse, including the dramatic 2023 board firing and the complex ethical questions surrounding artificial general intelligence.

1:05:59
Oct 7, 2025• Prof G Markets

AMD Rallies 24% on OpenAI Deal & Bari Weiss Takes Over CBS News

AMD's stock surges 24% after OpenAI announces a multibillion-dollar deal to secure six gigawatts of compute capacity, potentially gaining a 10% stake in the company, while Bari Weiss takes over as CBS News editor-in-chief after Paramount acquires her media startup, The Free Press.

38:50
Sep 26, 2025• Moonshots with Peter Diamandis

The Latest in AI: Job Loss, Elon & Sam Altman Chip Race & the "AI Bubble" w/ Brian Elliott (Blitzy), Emad Mostaque & Dave Blundin | EP #197

A dynamic discussion exploring AI's transformative potential across various sectors, including job markets, education, healthcare, and economic systems, highlighting rapid technological advancements and potential societal shifts.

1:43:13
Sep 8, 2025• Decoder with Nilay Patel

Sal Khan is hopeful that AI won't destroy education

Sal Khan discusses Khan Academy's evolution from simple math videos to a global learning platform, focusing on how AI could transform education by providing personalized, adaptive learning experiences while emphasizing that human teachers remain irreplaceable. He explores the potential of AI tutoring tools like Conmigo, which aim to support and enhance learning rather than replace human educators.

1:03:33